VU0029251 ≥98% (HPLC), powder Sigma V5390
Biochem/physiol Actions
VU0029251 is the first example of a partial mGluR5 partial antagonist that is not based on the MPEP scaffold. The compound displays a maximum inhibition of 50% activity, and cannot completely displace [3H] MPEP, suggesting that competition for MPEP is also allosteric, involving a unique site.
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Характеристики реактива | |
assay | ≥98% (HPLC) |
Molecular Formula | C10H11N3S2 |
storage temp. | 2-8°C |