VU 590 dihydrochloride hydrate ≥ (HPLC) Sigma V4265
Biochem/physiol Actions
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1 at low micromolar affinity, but it does not inhibit Kir2.1 or Kir4.1. VU590 appears to act by blocking the ion permeation pathway of the channel.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Характеристики реактива | |
assay | ≥ (HPLC) |
Molecular Formula | C24H32N4O7·2HCl · xH2O |
storage temp. | 2-8°C |