βCCt ≥98% (HPLC) Sigma SML0249
По запросу
Наличие: Срок поставки 60 дней
- Производитель: Sigma
- Каталожный номер:
SML0249 - CAS номер : 93835-05-3
Biochem/physiol Actions
βCCt has been characterized as an α1selective antagonist and benzodiazepine mixed agonist/antagonist.. A recent study found Ki values for the GABA-A subtypes were 0.72, 15, 18.9, 110.8, and >5,000 nM at five recombinant GABAA/BzR subtypes α1, α2, α3, α5, and α6 respectively. βCCt was a near ‘neutral’ antagonist (i.e., little or no efficacy) at all these 5 recombnant GABAA/BzR receptor subtypes. βCCt has been shown to reduce alcohol self-administration in alcohol preferring (P) and high alcohol drinking (HAD) rats.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Характеристики реактива | |
assay | ≥98% (HPLC) |
Molecular Formula | C16H16N2O2 |
storage temp. | 2-8°C |