β-Bungarotoxin from Bungarus multicinctus (Formosan Banded Krait) Sigma T5644
Preparation Note
β-Bungarotoxin is easily soluble in water.
Application
β-Bungarotoxin has been used to study the changes in its neurotoxic actions in the presence of suramin6. This toxin has also been used to analyze neuromuscular functions in rats7.
Biochem/physiol Actions
β-Bungarotoxin is reported to block potassium (K+) currents in frog and mouse motor nerves8. Furthermore, this toxin inhibits phorbol-ester-induced phosphorylation of synapsin I, GAP-43 and MARCKS in rat brains9.
Phospholipase A2 neurotoxin; destroys synaptic vesicles and inhibits acetylcholine release.
Характеристики реактива | |
storage temp. | −20°C |