Xanthine Oxidase from bovine milk lyophilized powder, 0.4-1.0 units/mg protein Sigma X4376
По запросу
- Производитель: Sigma
- Каталожный номер:
X4376 - CAS номер : 9002-17-9
Analysis Note
Protein determined by biuret
General description
Formerly E.C. 1.1.3.22
Packaging
5, 25, 50 units in poly bottle
Unit Definition
One unit will convert 1.0 μmole of xanthine to uric acid per min at pH 7.5 at 25 °C. Approx. 50% of the activity is obtained with hypoxanthine as substrate.
Physical form
Contains 0.5% sodium salicylate.
Biochem/physiol Actions
The isoflavanoid genistein was shown to inhibit xanthine oxidase at concentrations between 0.1-4.0 μM and then activate xanthine oxidase at concentrations higher than 5 μM. 1
Xanthine oxidase is a molybdenum-containing enzyme that is found in the cytosol, and may be strongly inhibited by flavonoids. It plays a vital role in the metabolism of some drugs, as well as purines and pyrimidines. It is also known to be a biological source of reactive oxygen species.
Характеристики реактива | |
storage temp. | 2-8°C |