Pimaricin preparation ~2.5%, aqueous suspension Sigma P0440
По запросу
Наличие: Срок поставки 60 дней
- Производитель: Sigma
- Каталожный номер:
P0440 - CAS номер : 7681-93-8
Biochem/physiol Actions
An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane.3
Application
Pimaricin is an amphoteric antibiotic from Streptomyces natalensis or S. chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. It is used to study pimaricin biosynthesis1 and as a fungicide in agar media2.
Характеристики реактива | |
Density (g/cm³) | 1.0 g/mL at 20 °C(lit.) |
Molecular Formula | C33H47NO13 |
storage temp. | 2-8°C |