Aprotinin from bovine lung Sigma A3886
По запросу
- Производитель: Sigma
- Каталожный номер:
A3886 - CAS номер : 9087-70-1
Application
Aprotinin is largely used as an inhibitor of trypsin.
Gel filtration molecular weight marker
Unit Definition
One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of Nalpha-benzoyl-DL-arginin
Biochem/physiol Actions
Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
Характеристики реактива | |
Molecular Formula | C284H432N84O79S7 |
storage temp. | −20°C |