Aprotinin from bovine lung lyophilized powder, 3-7 TIU/mg solid Sigma A4529
По запросу
- Производитель: Sigma
- Каталожный номер:
A4529 - CAS номер : 9087-70-1
Application
Aprotinin is largely used as an inhibitor of trypsin.
Packaging
1, 5 mg in glass bottle
10, 25 mg in poly bottle
100 mg in glass bottle
Preparation Note
This product is an affinity purified lyophilized powder purified to remove trace impurities. It has an activity of 3-7 TIU/mg.
Unit Definition
One Trypsin Inhibitor Unit (TIU) will decrease the activity of two trypsin units by 50%, where one trypsin unit will hydrolyze 1.0 μmole of Nalpha-benzoyl-DL-arginin
Biochem/physiol Actions
Aprotinin is a competitive serine protease inhibitor that forms stable complexes with and blocks the active sites of enzyme. This binding is reversible, and most aprotinin-protease complexes will dissociate at extreme pH levels >10 or <3. Structurally, Aprotinin is a monomeric globular protein derived from bovine lung that consists of 58 amino acids, arranged in a single polypeptide chain with three crosslinking disulfide bridges.
Характеристики реактива | |
Molecular Formula | C284H432N84O79S7 |
storage temp. | 2-8°C |