Z-Leu-Leu-Leu-al ≥90% (HPLC) Sigma C2211
По запросу
Наличие: Срок поставки 60 дней
- Производитель: Sigma
- Каталожный номер:
C2211 - CAS номер : 133407-82-6
Amino Acid Sequence
Z-Leu-Leu-Leu-al
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Packaging
5 mg in glass bottle
Biochem/physiol Actions
Potent, membrane-permeable proteasome inhibitor. Induces neurite outgrowth in PC12 cells at 10 μM. Blocks cleavage of poly(ADP-ribose) polymerase and apoptosis in thymocytes. Proteasome inhibition induces accumulation of heat shock protein mRNA, activation of heat-shock proteins, and enhanced thermotolerance in various cell types: however, it also activates JNK-1, which initiates apoptosis in response to cell stress.
Характеристики реактива | |
assay | ≥90% (HPLC) |
Molecular Formula | C26H41N3O5 |
storage temp. | −20°C |