Pimaricin from Streptomyces chattanoogensis, ≥95% (HPLC) Sigma P9703
По запросу
- Производитель: Sigma
- Каталожный номер:
P9703 - CAS номер : 7681-93-8
Biochem/physiol Actions
An antifungal polyene macrolide that binds specifically to ergosterol and blocks fungal growth. However, unlike nysatin and filipin, pimaricin does not change the permeability of the plasma membrane3
Packaging
25 mg in poly bottle
50, 100 mg in glass bottle
Application
Pimaricin is an amphoteric antibiotic from Streptomyces chattanoogensis. It is used for a variety of fungal infections, mainly topically. It is used as an ergosterol and cholesterol binding agent to study lipid bilayer dynamics, especially in fungal cells. Pimaricin is used as a fungicide in agar media. It is used to study the pleitropic regulator AdpAch 1 and the gamma-butyrolactone regulatory system of Streptomyces chattanoogensis2.
Характеристики реактива | |
assay | ≥95% (HPLC) |
Molecular Formula | C33H47NO13 |
storage temp. | 2-8°C |