Colupulone mixture of homologues, ≥85% (HPLC) Sigma 96681
Analysis Note
predominantly colupulone and lupulone
Biochem/physiol Actions
Colupulone is a bitter acid extracted from HOPS which activates transcription of xenobiotic metabolism via the human nuclear pregnane X receptor.
Mixture of predominantly colupulone and lupulone is an activator of the extrinsic apoptotic pathway via TRAIL DR4/DR5 death receptors and antimicrobial agent.
Protocols & Applications
Hops (Humulus lupulus) Plant Profile: bioactives, mechanism of action, references
Характеристики реактива | |
assay | ≥85% (HPLC) |
storage temp. | −20°C |