Blasticidine S hydrochloride ≥98.0% (HPLC) Sigma 15205
По запросу
- Производитель: Sigma
- Каталожный номер:
15205 - CAS номер : 3513-03-9
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Application
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Blasticidin S is used as a selection agent for transformed cells that contain the resistance genes bls, bsr, or BSD. Blasticidiin S has been used to select HEK293-T cells with TLR-2 constructs and HEK-D5 cells 1,2. It is also used to study protein synthesis at the level of peptide bond formation.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Biochem/physiol Actions
Blasticidin S inhibits hydrolysis of peptidyl-tRNA induced by release factors. It enhances the binding of tRNA to the large subunit of ribosomes and to an extent inhibits peptide bond formation.3
General description
Blasticidin S belongs to the aminoacylnucleoside class of antibiotics. It inhibits protein synthesis in bacteria and eukaryotes.3 It also has fungicidal properties and prevents rice blast disease.4
Protocols & Applications
Характеристики реактива | |
assay | ≥98.0% (HPLC) |
Molecular Formula | C17H26N8O5 · HCl |
storage temp. | −20°C |